Giant benign lymphangioendothelioma
Identifieur interne : 004777 ( Main/Exploration ); précédent : 004776; suivant : 004778Giant benign lymphangioendothelioma
Auteurs : Juan M. Revelles [Espagne] ; Jose L. Díaz [Espagne] ; Jorge Angulo [Espagne] ; Carlos Santonja [Espagne] ; Heinz Kutzner [Allemagne] ; Luis Requena [Espagne]Source :
- Journal of Cutaneous Pathology [ 0303-6987 ] ; 2012-10.
Abstract
Benign lymphangioendothelioma is a rare locally infiltrative vascular neoplasm, presenting as a slow‐growing, asymptomatic, reddish‐violaceous plaque. Histopathologically, it is characterized by irregular and thin‐walled vascular spaces, lined by a single and discontinuous layer of flat endothelial cells, dissecting dermal collagen bundles. We present the case of a 75‐year‐old man with a giant benign lymphangioendothelioma, to our knowledge, the largest example described in the literature. The immunohistochemical expression of Wilms tumor 1 gene is useful in vascular lesions to differentiate malformations from proliferative endothelial lesions. In our case, the positivity for WT1 supports the neoplastic nature of this lesion.
Url:
DOI: 10.1111/j.1600-0560.2012.01971.x
Affiliations:
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Histopathologically, it is characterized by irregular and thin‐walled vascular spaces, lined by a single and discontinuous layer of flat endothelial cells, dissecting dermal collagen bundles. We present the case of a 75‐year‐old man with a giant benign lymphangioendothelioma, to our knowledge, the largest example described in the literature. The immunohistochemical expression of Wilms tumor 1 gene is useful in vascular lesions to differentiate malformations from proliferative endothelial lesions. In our case, the positivity for WT1 supports the neoplastic nature of this lesion.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Revelles, Juan M" sort="Revelles, Juan M" uniqKey="Revelles J" first="Juan M." last="Revelles">Juan M. Revelles</name></region><name sortKey="Angulo, Jorge" sort="Angulo, Jorge" uniqKey="Angulo J" first="Jorge" last="Angulo">Jorge Angulo</name><name sortKey="Diaz, Jose L" sort="Diaz, Jose L" uniqKey="Diaz J" first="Jose L." last="Díaz">Jose L. Díaz</name><name sortKey="Requena, Luis" sort="Requena, Luis" uniqKey="Requena L" first="Luis" last="Requena">Luis Requena</name><name sortKey="Requena, Luis" sort="Requena, Luis" uniqKey="Requena L" first="Luis" last="Requena">Luis Requena</name><name sortKey="Santonja, Carlos" sort="Santonja, Carlos" uniqKey="Santonja C" first="Carlos" last="Santonja">Carlos Santonja</name></country><country name="Allemagne"><noRegion><name sortKey="Kutzner, Heinz" sort="Kutzner, Heinz" uniqKey="Kutzner H" first="Heinz" last="Kutzner">Heinz Kutzner</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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